DNA base flipping

id: dna-base-flipping-242-17732040
title: DNA base flipping
text: DNA base flipping, or nucleotide flipping, is a mechanism in which a single nucleotide base, or nucleobase, is rotated outside the nucleic acid double helix. This occurs when a nucleic acid-processing enzyme needs access to the base to perform work on it, such as its excision for replacement with another base during DNA repair. It was first observed in 1994 using X-ray crystallography in a methyltransferase enzyme catalyzing methylation of a cytosine base in DNA. Since then, it has been shown to
brand slug: wiki
category slug: encyclopedia
description: Biochemical process
original url: https://en.wikipedia.org/wiki/DNA_base_flipping
date created:
date modified: 2024-01-04T02:56:21Z
main entity: {"identifier":"Q17119064","url":"https://www.wikidata.org/entity/Q17119064"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/8a/Dna-base-flipping.svg","width":1250,"height":1097}
fields total: 13
integrity: 15

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