Discovery and development of proton pump inhibitors
id:
discovery-and-development-of-proton-pump-inhibitors-166-618415
title:
Discovery and development of proton pump inhibitors
text:
Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H+/K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease.
PPIs also can bind to other types of proton pumps such as those that occur in cancer cells and are finding applications in the reduction of cancer cell acid efflux and reduction of chemotherapy drug resistance.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Discovery_and_development_of_proton_pump_inhibitors
date created:
2010-11-05T12:00:42Z
date modified:
2024-08-29T17:31:44Z
main entity:
{"identifier":"Q5282005","url":"https://www.wikidata.org/entity/Q5282005"}
image:
fields total:
13
integrity:
14