Discovery and development of integrase inhibitors
id:
discovery-and-development-of-integrase-inhibitors-289-4819807
title:
Discovery and development of integrase inhibitors
text:
The first human immunodeficiency virus (HIV) case was reported in the United States in the early 1980s. Many drugs have been discovered to treat the disease but mutations in the virus and resistance to the drugs make development difficult. Integrase is a viral enzyme that integrates retroviral DNA into the host cell genome. Integrase inhibitors are a new class of drugs used in the treatment of HIV. The first integrase inhibitor, raltegravir, was approved in 2007 and other drugs were in clinical
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Discovery_and_development_of_integrase_inhibitors
date created:
date modified:
2023-11-29T08:34:23Z
main entity:
{"identifier":"Q5282001","url":"https://www.wikidata.org/entity/Q5282001"}
image:
fields total:
13
integrity:
13