Discovery and development of gliflozins
id:
discovery-and-development-of-gliflozins-286-3515113
title:
Discovery and development of gliflozins
text:
Gliflozins are a class of drugs in the treatment of type 2 diabetes (T2D). They act by inhibiting sodium/glucose cotransporter 2 (SGLT-2), and are therefore also called SGLT-2 inhibitors. The efficacy of the drug is dependent on renal excretion and prevents glucose from going into blood circulation by promoting glucosuria. The mechanism of action is insulin independent. Three drugs have been accepted by the Food and Drug Administration (FDA) in the United States; dapagliflozin, canagliflozin and
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Discovery_and_development_of_gliflozins
date created:
date modified:
2023-08-29T22:21:29Z
main entity:
{"identifier":"Q1429156","url":"https://www.wikidata.org/entity/Q1429156"}
image:
fields total:
13
integrity:
13