Discovery and development of direct thrombin inhibitors
id:
discovery-and-development-of-direct-thrombin-inhibitors-286-16038260
title:
Discovery and development of direct thrombin inhibitors
text:
Direct thrombin inhibitors (DTIs) are a class of anticoagulant drugs that can be used to prevent and treat embolisms and blood clots caused by various diseases. They inhibit thrombin, a serine protease which affects the coagulation cascade in many ways. DTIs have undergone rapid development since the 90's. With technological advances in genetic engineering the production of recombinant hirudin was made possible which opened the door to this new group of drugs. Before the use of DTIs the therapy
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Discovery_and_development_of_direct_thrombin_inhibitors
date created:
date modified:
2023-12-14T17:07:11Z
main entity:
{"identifier":"Q5281999","url":"https://www.wikidata.org/entity/Q5281999"}
image:
fields total:
13
integrity:
13