Discovery and development of cyclooxygenase 2 inhibitors

id: discovery-and-development-of-cyclooxygenase-2-inhibitors-288-18520067
title: Discovery and development of cyclooxygenase 2 inhibitors
text: Cyclooxygenases are enzymes that take part in a complex biosynthetic cascade that results in the conversion of polyunsaturated fatty acids to prostaglandins and thromboxane(s). Their main role is to catalyze the transformation of arachidonic acid into the intermediate prostaglandin H2, which is the precursor of a variety of prostanoids with diverse and potent biological actions. Cyclooxygenases have two main isoforms that are called COX-1 and COX-2. COX-1 is responsible for the synthesis of pros
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Discovery_and_development_of_cyclooxygenase_2_inhibitors
date created:
date modified: 2023-06-04T13:48:42Z
main entity: {"identifier":"Q5281998","url":"https://www.wikidata.org/entity/Q5281998"}
image:
fields total: 13
integrity: 13

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