Directed evolution

id: directed-evolution-286-747843
title: Directed evolution
text: Directed evolution (DE) is a method used in protein engineering that mimics the process of natural selection to steer proteins or nucleic acids toward a user-defined goal. It consists of subjecting a gene to iterative rounds of mutagenesis, selection and amplification. It can be performed in vivo, or in vitro. Directed evolution is used both for protein engineering as an alternative to rationally designing modified proteins, as well as for experimental evolution studies of fundamental evolutiona
brand slug: wiki
category slug: encyclopedia
description: Protein engineering method
original url: https://en.wikipedia.org/wiki/Directed_evolution
date created:
date modified: 2024-02-03T04:28:37Z
main entity: {"identifier":"Q440681","url":"https://www.wikidata.org/entity/Q440681"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/84/DE_cycle.png","width":1875,"height":1326}
fields total: 13
integrity: 15

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