Dipeptidyl peptidase-4 inhibitor

id: dipeptidyl-peptidase-4-inhibitor-321-129678
title: Dipeptidyl peptidase-4 inhibitor
text: Inhibitors of dipeptidyl peptidase 4 are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006. Glucagon increases blood glucose levels, and DPP-4 inhibitors reduce glucagon and blood glucose levels. The mechanism of DPP-4 inhibitors is to increase incretin levels, which inhibit glucagon release, which in turn increases insulin secretion,
brand slug: wiki
category slug: encyclopedia
description: Enzyme blocker and diabetes treatment drug
original url: https://en.wikipedia.org/wiki/Dipeptidyl_peptidase-4_inhibitor
date created:
date modified: 2024-02-01T07:40:30Z
main entity: {"identifier":"Q419770","url":"https://www.wikidata.org/entity/Q419770"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/64/Incretins_and_DPP_4_inhibitors.svg","width":522,"height":317}
fields total: 13
integrity: 15

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