Dimroth rearrangement

id: dimroth-rearrangement-264-3676948
title: Dimroth rearrangement
text: The Dimroth rearrangement is a rearrangement reaction taking place with certain 1,2,3-triazoles where endocyclic and exocyclic nitrogen atoms switch place. This organic reaction was discovered in 1909 by Otto Dimroth. With R a phenyl group the reaction takes place in boiling pyridine for 24 hours. This type of triazole has an amino group in the 5 position. After ring-opening to a diazo intermediate, C-C bond rotation is possible with 1,3-migration of a proton. Certain 1-alkyl-2-iminopyrimidines
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original url: https://en.wikipedia.org/wiki/Dimroth_rearrangement
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date modified: 2022-10-27T19:36:07Z
main entity: {"identifier":"Q902659","url":"https://www.wikidata.org/entity/Q902659"}
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