Dihydropyrimidine dehydrogenase (NADP+)
id:
dihydropyrimidine-dehydrogenase-nadp-234-14641917
title:
Dihydropyrimidine dehydrogenase (NADP+)
text:
In enzymology, a dihydropyrimidine dehydrogenase (NADP+) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 5,6-dihydrouracil and NADP+, whereas its 3 products are uracil, NADPH, and H+. In humans the enzyme is encoded by the DPYD gene. It is the initial and rate-limiting step in pyrimidine catabolism. It catalyzes the reduction of uracil and thymine. It is also involved in the degradation of the chemotherapeutic drugs 5-fluorouracil and tegafur. It als
brand slug:
wiki
category slug:
encyclopedia
description:
Class of enzymes
original url:
https://en.wikipedia.org/wiki/Dihydropyrimidine_dehydrogenase_(NADP%2B)
date created:
date modified:
2023-12-22T22:05:31Z
main entity:
{"identifier":"Q1114455","url":"https://www.wikidata.org/entity/Q1114455"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/58/1gte.jpg","width":1000,"height":797}
fields total:
13
integrity:
15