Dihydropyrimidine dehydrogenase deficiency
id:
dihydropyrimidine-dehydrogenase-deficiency-234-9298483
title:
Dihydropyrimidine dehydrogenase deficiency
text:
Dihydropyrimidine dehydrogenase deficiency is an autosomal recessive
metabolic disorder in which there is absent or significantly decreased activity of dihydropyrimidine dehydrogenase, an enzyme involved in the metabolism of uracil and thymine. Individuals with this condition may develop life-threatening toxicity following exposure to 5-fluorouracil (5-FU), a chemotherapy drug that is used in the treatment of cancer. Beside 5-FU, widely prescribed oral fluoropyrimidine capecitabine (Xeloda) coul
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Dihydropyrimidine_dehydrogenase_deficiency
date created:
date modified:
2023-11-16T22:22:29Z
main entity:
{"identifier":"Q5276448","url":"https://www.wikidata.org/entity/Q5276448"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f1/Autosomal_recessive_-_en.svg","width":738,"height":1283}
fields total:
13
integrity:
15