Dickkopf
id:
dickkopf-320-2637688
title:
Dickkopf
text:
Dickkopf (DKK) is a family of proteins consisting of five members as of 2020. That is, vertebrates usually contain five genes that are members of the family. The most well-studied is Dickkopf-related protein 1 (DKK1). DKK proteins inhibit the Wnt signaling pathway coreceptors LRP5 and LRP6. They bind with high affinity as ligands to KREMEN1 and KREMEN2, which are transmembrane proteins. DKK proteins have important roles in the development of vertebrates.
brand slug:
wiki
category slug:
encyclopedia
description:
Family of proteins
original url:
https://en.wikipedia.org/wiki/Dickkopf
date created:
date modified:
2024-02-17T13:22:04Z
main entity:
{"identifier":"Q60965136","url":"https://www.wikidata.org/entity/Q60965136"}
image:
fields total:
13
integrity:
14