Diarylquinoline
id:
diarylquinoline-233-9650273
title:
Diarylquinoline
text:
Diaryl quinolines (DARQs) are a chemical class of drugs that treat tuberculosis. They target subunit c of mycobacterial ATP synthase, inhibiting the enzyme so mycobacterium tuberculosis cannot synthesise ATP. This effectively kills the bacteria. Although ATP synthase in bacteria is similar to its eukaryotic analogue, diarylquinoline agents are very specific to the bacterial enzyme, so were expected to be safe for use in humans and other eukaryotes. This also suggests that bacterial ATP synthase
brand slug:
wiki
category slug:
encyclopedia
description:
Class of bacteria
original url:
https://en.wikipedia.org/wiki/Diarylquinoline
date created:
date modified:
2024-03-08T13:15:02Z
main entity:
{"identifier":"Q16899782","url":"https://www.wikidata.org/entity/Q16899782"}
image:
fields total:
13
integrity:
14