Diarylpropionitrile
id:
diarylpropionitrile-233-7572597
title:
Diarylpropionitrile
text:
Diarylpropionitrile (DPN), also known as 2,3-bis(p-hydroxyphenyl)propionitrile (2,3-BHPPN), is a synthetic, nonsteroidal, and highly selective agonist of ERβ that is used widely in scientific research to study the function of this receptor. It is 70-fold more selective for ERβ over ERα, and has 100-fold lower affinity for GPER (GPR30) relative to estradiol. DPN produces antidepressant- and anxiolytic-like effects in animals via activation of the endogenous oxytocin system. First reported in 2001
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Diarylpropionitrile
date created:
date modified:
2023-12-26T17:44:09Z
main entity:
{"identifier":"Q25100751","url":"https://www.wikidata.org/entity/Q25100751"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5d/Diarylpropionitrile.svg","width":324,"height":272}
fields total:
13
integrity:
15