Desmethylclozapine
id:
desmethylclozapine-248-7483064
title:
Desmethylclozapine
text:
N-Desmethylclozapine (NDMC), or norclozapine, is a major active metabolite of the atypical antipsychotic drug clozapine. Unlike clozapine, it possesses intrinsic activity at the D2/D3 receptors, and acts as a weak partial agonist at these sites similarly to aripiprazole and bifeprunox. Notably, NDMC has also been shown to act as a potent and efficacious agonist at the M1 and δ-opioid receptors, unlike clozapine as well. It was hypothesized that on account of these unique actions, NDMC might unde
brand slug:
wiki
category slug:
encyclopedia
description:
Active metabolite of the drug clozapine
original url:
https://en.wikipedia.org/wiki/Desmethylclozapine
date created:
date modified:
2023-10-28T23:54:24Z
main entity:
{"identifier":"Q5264612","url":"https://www.wikidata.org/entity/Q5264612"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/fd/Desmethylclozapine.svg","width":512,"height":478}
fields total:
13
integrity:
15