Demecolcine
id:
demecolcine-309-5545249
title:
Demecolcine
text:
Demecolcine is a drug used in chemotherapy. It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation, thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed. During cell division, demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically, demecolcine has been used to improve t
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Demecolcine
date created:
date modified:
2023-11-21T05:17:50Z
main entity:
{"identifier":"Q903666","url":"https://www.wikidata.org/entity/Q903666"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b2/Demecolcine.png","width":918,"height":811}
fields total:
13
integrity:
15