Delépine reaction

id: del-pine-reaction-251-9857814
title: Delépine reaction
text: The Delépine reaction is the organic synthesis of primary amines (4) by reaction of benzyl or alkyl halides (1) with hexamethylenetetramine (2) followed by acid hydrolysis of the quaternary ammonium salt (3). It is named after the French chemist Stéphane Marcel Delépine (1871–1965). Advantages of this reaction are selective access to the primary amine without side reactions from easily accessible reactants with short reaction times and relatively mild reaction conditions. Downsides include that
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Del%C3%A9pine_reaction
date created:
date modified: 2022-04-29T13:01:27Z
main entity: {"identifier":"Q451915","url":"https://www.wikidata.org/entity/Q451915"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/e/e3/Delepine2.png","width":1237,"height":447}
fields total: 13
integrity: 14

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