Defective interfering particle

id: defective-interfering-particle-242-360886
title: Defective interfering particle
text: Defective interfering particles (DIPs), also known as defective interfering viruses, are spontaneously generated virus mutants in which a critical portion of the particle's genome has been lost due to defective replication or non-homologous recombination. The mechanism of their formation is presumed to be as a result of template-switching during replication of the viral genome, although non-replicative mechanisms involving direct ligation of genomic RNA fragments have also been proposed. DIPs ar
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Defective_interfering_particle
date created:
date modified: 2024-04-11T23:34:35Z
main entity: {"identifier":"Q5251124","url":"https://www.wikidata.org/entity/Q5251124"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5b/RF00496.jpg","width":452,"height":452}
fields total: 13
integrity: 14

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