Daf-8

id: daf-8-292-17317323
title: Daf-8
text: The DAF-8 nematode gene encoding a R-SMAD protein of TGF-beta signaling pathway, which was originally found in model organism Caenorhabditis elegans. When the TGF-β ligand daf-7 binds to the TGF-β receptors daf-1/daf-4 on the surface of nematode cell, daf-8 will be phosphorylated and forms a heterodimer with daf-14, then enter to the nucleus to inhibit transcription regulated by daf-3/daf-5.
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Daf-8
date created:
date modified: 2023-12-02T21:37:49Z
main entity: {"identifier":"Q29663203","url":"https://www.wikidata.org/entity/Q29663203"}
image:
fields total: 13
integrity: 13

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