D5SICS
id:
d5sics-285-11094883
title:
D5SICS
text:
d5SICS is an artificial nucleoside containing 6-methylisoquinoline-1-thione-2-yl group instead of a base. It pairs up with dNaM in a hydrophobic interaction. It was not able to be removed by the error-correcting machinery of the E. coli into which it was inserted. The pairing of d5SICS–dNaM is mediated by packing and hydrophobic forces instead of hydrogen bonding, which occurs in natural base pairs. Therefore, in free DNA, rings of d5SICS and dNaM are placed in parallel planes instead of the sam
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/D5SICS
date created:
date modified:
2023-04-30T17:06:07Z
main entity:
{"identifier":"Q25323746","url":"https://www.wikidata.org/entity/Q25323746"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/8/8c/D5SICS-skeletal.png","width":801,"height":1109}
fields total:
13
integrity:
15