Cytolethal distending toxin
id:
cytolethal-distending-toxin-167-2109875
title:
Cytolethal distending toxin
text:
Cytolethal distending toxins are a class of heterotrimeric toxins produced by certain gram-negative bacteria that display DNase activity. These toxins trigger G2/M cell cycle arrest in specific mammalian cell lines, leading to the enlarged or distended cells for which these toxins are named. Affected cells die by apoptosis. Each toxin consists of three distinct subunits named alphabetically in the order that their coding genes appear in the cdt operon. Cytolethal distending toxins are classified
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Cytolethal_distending_toxin
date created:
2011-06-28T14:54:55Z
date modified:
2024-08-30T04:50:18Z
main entity:
{"identifier":"Q5201358","url":"https://www.wikidata.org/entity/Q5201358"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/en/8/8a/PDB_protein_1sr4_%28HdCDT%29.jpg","width":500,"height":500}
fields total:
13
integrity:
15