Cytochrome P450 oxidoreductase deficiency
id:
cytochrome-p450-oxidoreductase-deficiency-275-11975596
title:
Cytochrome P450 oxidoreductase deficiency
text:
Cytochrome P450 oxidoreductase deficiency (PORD) is a rare disease and inborn error of metabolism caused by deficiency of cytochrome P450 oxidoreductase (POR). POR is a 2-flavin protein that is responsible for the transfer of electrons from NADPH to all 50 microsomal cytochrome P450 (CYP450) enzymes. This includes the steroidogenic enzymes CYP17A1 (17α-hydroxylase/17,20-lyase), CYP19A1 (aromatase), and CYP21A2 (21-hydroxylase); CYP26B1; and the hepatic drug-metabolizing CYP450 enzymes, among man
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Cytochrome_P450_oxidoreductase_deficiency
date created:
date modified:
2023-12-10T15:46:44Z
main entity:
{"identifier":"Q56694535","url":"https://www.wikidata.org/entity/Q56694535"}
image:
fields total:
13
integrity:
14