Cytochrome b5 deficiency
id:
cytochrome-b5-deficiency-233-14151273
title:
Cytochrome b5 deficiency
text:
Cytochrome b5 deficiency is a rare condition and form of isolated 17,20-lyase deficiency caused by deficiency in cytochrome b5, a small hemoprotein that acts as an allosteric factor to facilitate the interaction of CYP17A1 (17α-hydroxylase/17,20-lyase) with P450 oxidoreductase (POR), thereby allowing for the 17,20-lyase activity of CYP17A1. The condition affects both adrenal and gonadal androgen biosynthesis and results in male pseudohermaphroditism. The principal biological role of cytochrome b
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Cytochrome_b5_deficiency
date created:
date modified:
2023-10-31T01:12:27Z
main entity:
{"identifier":"Q56694604","url":"https://www.wikidata.org/entity/Q56694604"}
image:
fields total:
13
integrity:
14