Cyclophellitol
id:
cyclophellitol-251-3969574
title:
Cyclophellitol
text:
Cyclophellitol is a potent irreversible inhibitor of beta-glucosidases. It is a cyclitol mimic of beta-glucose with an epoxide group in place of the acetal group found in glucosides. When recognized, cyclophellitol undergoes an acid-catalyzed ring-opening addition reaction with the catalytic nucleophile of a retaining glycoside hydrolase. The resulting ester linkage cannot be hydrolyzed by the normal catalytic machinery of the enzyme, resulting in irreversible inhibition. Cyclophellitol was orig
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Cyclophellitol
date created:
date modified:
2021-05-09T18:39:18Z
main entity:
{"identifier":"Q77502129","url":"https://www.wikidata.org/entity/Q77502129"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/38/Cyclophellitol.png","width":290,"height":258}
fields total:
13
integrity:
15