Cycloguanil
id:
cycloguanil-187-15525255
title:
Cycloguanil
text:
Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil. However, more recent work has indicated that, while proguanil is synergistic with the drug atovaquone, cycloguanil is in fact antagonistic to the effects of atovaquone, suggesting that, unlike cycloguanil, proguanil may have an alternative mechanism of antimalarial action besides
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Cycloguanil
date created:
2007-08-02T04:31:31Z
date modified:
2024-09-08T15:52:05Z
main entity:
{"identifier":"Q5198706","url":"https://www.wikidata.org/entity/Q5198706"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/1/18/Cycloguanil.svg","width":512,"height":282}
fields total:
13
integrity:
16