Cyclic guanosine monophosphate–adenosine monophosphate
id:
cyclic-guanosine-monophosphate-adenosine-monophosphate-236-877918
title:
Cyclic guanosine monophosphate–adenosine monophosphate
text:
Cyclic guanosine monophosphate–adenosine monophosphate is the first cyclic di-nucleotide found in metazoa. In mammalian cells, cGAMP is synthesized by cyclic GMP-AMP synthase (cGAS) from ATP and GTP upon cytosolic DNA stimulation. cGAMP produced by cGAS contains mixed phosphodiester linkages, with one between 2'-OH of GMP and 5'-phosphate of AMP and the other between 3'-OH of AMP and 5'-phosphate of GMP. This molecule, referred to as 2′3′-cGAMP, functions as an endogenous second messenger induci
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Cyclic_guanosine_monophosphate%E2%80%93adenosine_monophosphate
date created:
date modified:
2023-02-19T18:46:03Z
main entity:
{"identifier":"Q17143195","url":"https://www.wikidata.org/entity/Q17143195"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/30/Cyclic_guanosine_monophosphate-adenosine_monophosphate.svg","width":512,"height":382}
fields total:
13
integrity:
15