CpG island hypermethylation
id:
cpg-island-hypermethylation-263-10317027
title:
CpG island hypermethylation
text:
CpG island hypermethylation is a phenomenon that is important for the regulation of gene expression in cancer cells, as an epigenetic control aberration responsible for gene inactivation. Hypermethylation of CpG islands has been described in almost every type of tumor. Many important cellular pathways, such as DNA repair, cell cycle (p14ARF), apoptosis (DAPK), and cell adherence, are inactivated by it. Hypermethylation is linked to methyl-binding proteins, DNA methyltransferases and histone deac
brand slug:
wiki
category slug:
encyclopedia
description:
Phenomenon
original url:
https://en.wikipedia.org/wiki/CpG_island_hypermethylation
date created:
date modified:
2024-01-25T07:48:11Z
main entity:
{"identifier":"Q30672955","url":"https://www.wikidata.org/entity/Q30672955"}
image:
fields total:
13
integrity:
14