Copper-free click chemistry
id:
copper-free-click-chemistry-201-11683819
title:
Copper-free click chemistry
text:
Copper-free click chemistry is a bioorthogonal reaction as a variant of an azide-alkyne Huisgen cycloaddition. By eliminating cytotoxic copper catalysts, the reaction proceeds without live-cell toxicity. It was developed as a faster alternative to the Staudinger ligation with the first generation of Cu-free click chemistry, producing rate constants over 63 times faster. Although the reaction produces a regioisomeric mixture of triazoles, the lack of regioselectivity in the reaction is not a majo
brand slug:
wiki
category slug:
encyclopedia
description:
Type of chemical reaction
original url:
https://en.wikipedia.org/wiki/Copper-free_click_chemistry
date created:
date modified:
2023-01-17T21:57:14Z
main entity:
{"identifier":"Q5168679","url":"https://www.wikidata.org/entity/Q5168679"}
image:
fields total:
13
integrity:
14