Conrad–Limpach synthesis
id:
conrad-limpach-synthesis-163-3062965
title:
Conrad–Limpach synthesis
text:
The Conrad–Limpach synthesis is the condensation of anilines (1) with β-ketoesters (2) to form 4-hydroxyquinolines (4) via a Schiff base (3). The overall reaction type is a combination of both an addition reaction as well as a rearrangement reaction. This reaction was discovered by Max Conrad (1848–1920) and Leonhard Limpach (1852–1933) in 1887 while they were studying the synthesis of quinoline derivatives.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Conrad%E2%80%93Limpach_synthesis
date created:
2006-06-27T00:39:05Z
date modified:
2024-08-28T03:20:39Z
main entity:
{"identifier":"Q1944895","url":"https://www.wikidata.org/entity/Q1944895"}
image:
fields total:
13
integrity:
14