Congenital disorder of glycosylation type IIc
id:
congenital-disorder-of-glycosylation-type-iic-319-1610910
title:
Congenital disorder of glycosylation type IIc
text:
Congenital disorder of glycosylation type IIc or Leukocyte adhesion deficiency-2 (LAD2) is a type of leukocyte adhesion deficiency attributable to the absence of neutrophil sialyl-LewisX, a ligand of P- and E-selectin on vascular endothelium. It is associated with SLC35C1. This disorder was discovered in two unrelated Israeli boys 3 and 5 years of age, each the offspring of consanguineous parents. Both had severe mental retardation, short stature, a distinctive facial appearance, and the Bombay
brand slug:
wiki
category slug:
encyclopedia
description:
Medical condition
original url:
https://en.wikipedia.org/wiki/Congenital_disorder_of_glycosylation_type_IIc
date created:
date modified:
2022-08-22T17:09:15Z
main entity:
{"identifier":"Q5160418","url":"https://www.wikidata.org/entity/Q5160418"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f1/Autosomal_recessive_-_en.svg","width":738,"height":1283}
fields total:
13
integrity:
15