Condensation domain
id:
condensation-domain-313-4965051
title:
Condensation domain
text:
In molecular biology, the condensation domain is a protein domain found in many multi-domain enzymes which synthesise peptide antibiotics. This domain catalyses a condensation reaction to form peptide bonds in non-ribosomal peptide biosynthesis. It is usually found to the carboxy side of a phosphopantetheine binding domain (pp-binding). It has been shown that mutations in the HHXXXDG sequence motif in this domain abolish activity suggesting this is part of the active site.
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Condensation_domain
date created:
date modified:
2020-12-20T00:51:57Z
main entity:
{"identifier":"Q24779676","url":"https://www.wikidata.org/entity/Q24779676"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/b1/PDB_1l5a_EBI.jpg","width":800,"height":600}
fields total:
13
integrity:
14