Clozapine N-oxide

id: clozapine-n-oxide-250-1234149
title: Clozapine N-oxide
text: Clozapine N-oxide (CNO) is a synthetic drug used mainly in biomedical research as a ligand to activate DREADD receptors. Although CNO was initially believed to be biologically inert. However, it has been shown not to enter the brain after administration and to reverse metabolise in peripheral tissues to form clozapine. Clozapine can bind to a number of different serotonergic, dopaminergic and adrenergic receptors within the brain. Therefore, behavioural data using the CNO-DREADD system in neuros
brand slug: wiki
category slug: encyclopedia
description: Chemical compound
original url: https://en.wikipedia.org/wiki/Clozapine_N-oxide
date created:
date modified: 2024-01-18T07:20:22Z
main entity: {"identifier":"Q27284305","url":"https://www.wikidata.org/entity/Q27284305"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/0c/Clozapine_N-oxide.png","width":1212,"height":1099}
fields total: 13
integrity: 15

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