Cieplak effect
id:
cieplak-effect-236-14306411
title:
Cieplak effect
text:
In organic chemistry, the Cieplak effect is a predictive model to rationalize why nucleophiles preferentially add to one face of a carbonyl over another. Proposed by Andrzej Stanislaw Cieplak in 1980, it correctly predicts results that could not be justified by the other standard models at the time, such as the Cram and Felkin–Anh models. In the Cieplak model, electrons from a neighboring bond delocalize into the forming carbon–nucleophile (C–Nuc) bond, lowering the energy of the transition stat
brand slug:
wiki
category slug:
encyclopedia
description:
Predictive model in organic chemistry
original url:
https://en.wikipedia.org/wiki/Cieplak_effect
date created:
date modified:
2023-06-25T22:59:50Z
main entity:
{"identifier":"Q25111175","url":"https://www.wikidata.org/entity/Q25111175"}
image:
fields total:
13
integrity:
14