Centrosome cycle

id: centrosome-cycle-220-1246589
title: Centrosome cycle
text: Centrosomes are the major microtubule organizing centers (MTOC) in mammalian cells. Failure of centrosome regulation can cause mistakes in chromosome segregation and is associated with aneuploidy. A centrosome is composed of two orthogonal cylindrical protein assemblies, called centrioles, which are surrounded by a protein dense amorphous cloud of pericentriolar material (PCM). The PCM is essential for nucleation and organization of microtubules. The centrosome cycle is important to ensure that
brand slug: wiki
category slug: encyclopedia
description: Centrioles are nine triplets microtubules
original url: https://en.wikipedia.org/wiki/Centrosome_cycle
date created: 2011-04-20T05:20:46Z
date modified: 2024-09-13T13:47:35Z
main entity: {"identifier":"Q5063037","url":"https://www.wikidata.org/entity/Q5063037"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/7/7a/Centrosome_Cycle.svg","width":3220,"height":2300}
fields total: 13
integrity: 16

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