Cellular thermal shift assay
id:
cellular-thermal-shift-assay-195-11763699
title:
Cellular thermal shift assay
text:
CEllular Thermal Shift Assay (CETSA®) is a patented label free chemoproteomics method that has enabled measurements of compound target engagement in intact cells and tissue, without modifications to the target protein. This is accomplished by comparing the measured cellular thermal stability of the protein in the presence and absence of the test compound. An efficacious compound binding to its intended target will affect associated proteins and thereby leave traces in the cell in form of changed
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Cellular_thermal_shift_assay
date created:
date modified:
2024-01-04T03:00:54Z
main entity:
{"identifier":"Q96374623","url":"https://www.wikidata.org/entity/Q96374623"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/d/d7/The_CETSA%C2%AE_method_.png","width":8314,"height":5764}
fields total:
13
integrity:
14