CD25 deficiency

id: cd25-deficiency-317-9181286
title: CD25 deficiency
text: CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene. The mutations cause expression of a defective α chain or complete absence thereof, an essential part of high-affinity interleukin-2 (IL-2) receptors. The result is a syndrome described as IPEX-like or a SCID. In one patient, deficiency of CD25 on CD4+ lymphocytes caused significantly impaired sensitivity to IL-2. This was de
brand slug: wiki
category slug: encyclopedia
description: Medical condition
original url: https://en.wikipedia.org/wiki/CD25_deficiency
date created:
date modified: 2024-03-18T09:36:40Z
main entity: {"identifier":"Q5009803","url":"https://www.wikidata.org/entity/Q5009803"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f1/Autosomal_recessive_-_en.svg","width":738,"height":1283}
fields total: 13
integrity: 15

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