Catecholaldehyde hypothesis
id:
catecholaldehyde-hypothesis-188-15511664
title:
Catecholaldehyde hypothesis
text:
The catecholaldehyde hypothesis is a scientific theory positing that neurotoxic aldehyde metabolites of the catecholamine neurotransmitters dopamine and norepinephrine are responsible for neurodegenerative diseases involving loss of catecholaminergic neurons, for instance Parkinson's disease. The specific metabolites thought to be involved include 3,4-dihydroxyphenylacetaldehyde (DOPAL) and 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), which are formed from dopamine and norepinephrine by monoamin
brand slug:
wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Catecholaldehyde_hypothesis
date created:
2018-05-12T04:21:47Z
date modified:
2024-09-09T00:05:51Z
main entity:
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f3/Dihydroxyphenylacetaldehyde.png","width":710,"height":304}
fields total:
13
integrity:
14