Castro–Stephens coupling
id:
castro-stephens-coupling-241-11635179
title:
Castro–Stephens coupling
text:
The Castro–Stephens coupling is a cross coupling reaction between a copper(I) acetylide and an aryl halide in pyridine, forming a disubstituted alkyne and a copper(I) halide. The reaction was described in 1963 by chemists Castro and Stephens. The reaction is similar to the much older Rosenmund–von Braun synthesis (1914) between aryl halides and copper(I) cyanide and was itself modified in 1975 as the Sonogashira coupling by adding a palladium catalyst and preparing the organocopper compound in s
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wiki
category slug:
encyclopedia
description:
original url:
https://en.wikipedia.org/wiki/Castro%E2%80%93Stephens_coupling
date created:
date modified:
2024-01-31T23:41:46Z
main entity:
{"identifier":"Q902696","url":"https://www.wikidata.org/entity/Q902696"}
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fields total:
13
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13