Caretaker gene
id:
caretaker-gene-320-2876366
title:
Caretaker gene
text:
Caretaker genes encode products that stabilize the genome. Fundamentally, mutations in caretaker genes lead to genomic instability. Tumor cells arise from two distinct classes of genomic instability: mutational instability arising from changes in the nucleotide sequence of DNA and chromosomal instability arising from improper rearrangement of chromosomes. Changes in the genome that allow uncontrolled cell proliferation or cell immortality are responsible for cancer. It is believed that the major
brand slug:
wiki
category slug:
encyclopedia
description:
Genes that encode genome-stabilizing products
original url:
https://en.wikipedia.org/wiki/Caretaker_gene
date created:
date modified:
2023-08-03T06:12:35Z
main entity:
{"identifier":"Q5039065","url":"https://www.wikidata.org/entity/Q5039065"}
image:
fields total:
13
integrity:
14