Carbonic anhydrase 9

id: carbonic-anhydrase-9-291-16985538
title: Carbonic anhydrase 9
text: Carbonic anhydrase IX is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid secretion in the gastrointestinal tract. CA IX is overexpressed in many types of cancer including clear cell renal cell carcinoma (RCC) as well as carcinomas of the cervix, breast and lung where it promotes tumor growth by enhancing tumor acidosis.
brand slug: wiki
category slug: encyclopedia
description: Enzyme found in humans
original url: https://en.wikipedia.org/wiki/Carbonic_anhydrase_9
date created:
date modified: 2024-02-03T04:01:20Z
main entity: {"identifier":"Q17854517","url":"https://www.wikidata.org/entity/Q17854517"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5a/Protein_CA9_PDB_2HKF.png","width":1200,"height":1000}
fields total: 13
integrity: 15

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