Calcineurin
id:
calcineurin-165-15728788
title:
Calcineurin
text:
Calcineurin (CaN) is a calcium and calmodulin dependent serine/threonine protein phosphatase. It activates the T cells of the immune system and can be blocked by drugs. Calcineurin activates nuclear factor of activated T cell cytoplasmic (NFATc), a transcription factor, by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, in turn, stimulates the growth and differentiation of the T cell response. Ca
brand slug:
wiki
category slug:
encyclopedia
description:
Class of enzymes
original url:
https://en.wikipedia.org/wiki/Calcineurin
date created:
2004-08-26T19:15:23Z
date modified:
2024-08-30T01:10:13Z
main entity:
{"identifier":"Q420566","url":"https://www.wikidata.org/entity/Q420566"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/06/Protein_PPP3CA_PDB_1aui.png","width":947,"height":538}
fields total:
13
integrity:
16