CA77.1
id:
ca77-1-208-4056822
title:
CA77.1
text:
CA77.1 (CA) is a synthetic compound that activates chaperone-mediated autophagy (CMA) by increasing the expression of the lysosomal receptor for this pathway, LAMP2A, in lysosomes. CA77.1 is a derivative of earlier compound AR7(HY-101106), which shows potent CMA activation in vitro but is not suitable for in vivo use. CA77.1 is able to activate CMA in vivo, and demonstrates brain penetrance and favorable pharmacokinetics. It has been shown in animal studies that in vivo administration of CA77.1
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/CA77.1
date created:
2021-05-14T19:02:59Z
date modified:
2024-09-11T07:39:01Z
main entity:
{"identifier":"Q106863577","url":"https://www.wikidata.org/entity/Q106863577"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/02/CA77-1_structure.png","width":1713,"height":831}
fields total:
13
integrity:
16