C-myc internal ribosome entry site (IRES)

id: c-myc-internal-ribosome-entry-site-ires-322-16751531
title: C-myc internal ribosome entry site (IRES)
text: The c-myc internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of C-myc and allows cap-independent translation. The mammalian c-myc gene is a proto-oncogene which is required for cell proliferation, transformation and death. c-myc mRNA has an alternative method of translation via internal ribosome entry where ribosomes are recruited to the IRES located in the 5' UTR thus bypassing the typical eukaryotic cap-dependent translation pathway.
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/C-myc_internal_ribosome_entry_site_(IRES)
date created:
date modified: 2019-10-03T22:39:06Z
main entity: {"identifier":"Q5005953","url":"https://www.wikidata.org/entity/Q5005953"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/bb/RF00216.jpg","width":452,"height":452}
fields total: 13
integrity: 14

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