Buprenorphine/samidorphan
id:
buprenorphine-samidorphan-248-8353871
title:
Buprenorphine/samidorphan
text:
Buprenorphine/samidorphan is a combination formulation of buprenorphine and samidorphan which is under development as an add on to antidepressants in treatment-resistant depression (TRD). ALKS-5461 failed to meet its primary efficacy endpoints in two trials from 2016. On the basis of a third study that did meet its primary endpoints, Alkermes initiated a rolling New Drug Application with the FDA. In November 2018, an FDA panel voted against recommending approval, finding that evidence was insuff
brand slug:
wiki
category slug:
encyclopedia
description:
Combination drug formulation
original url:
https://en.wikipedia.org/wiki/Buprenorphine/samidorphan
date created:
date modified:
2023-11-05T02:21:20Z
main entity:
{"identifier":"Q18204530","url":"https://www.wikidata.org/entity/Q18204530"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/31/Buprenorphine_and_samidorphan.svg","width":512,"height":879}
fields total:
13
integrity:
15