BUB1B
id:
bub1b-309-13326892
title:
BUB1B
text:
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene. Also known as BubR1, this protein is recognized for its mitotic roles in the spindle assembly checkpoint (SAC) and kinetochore-microtubule interactions that facilitate chromosome migration and alignment. BubR1 promotes mitotic fidelity and protects against aneuploidy by ensuring proper chromosome segregation between daughter cells. BubR1 is proposed to prevent tumorigenesis.
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/BUB1B
date created:
date modified:
2023-12-22T21:43:41Z
main entity:
{"identifier":"Q17853927","url":"https://www.wikidata.org/entity/Q17853927"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/07/Ideogram_human_chromosome_15.svg","width":474,"height":189}
fields total:
13
integrity:
15