Brequinar
id:
brequinar-161-2484203
title:
Brequinar
text:
Brequinar (DuP-785) is a drug that acts as a potent and selective inhibitor of the enzyme dihydroorotate dehydrogenase. It blocks synthesis of pyrimidine based nucleotides in the body and so inhibits cell growth. Brequinar was invented by DuPont Pharmaceuticals in the 1980s. In 2001, Bristol-Myers Squibb acquired DuPont, and in 2017, Clear Creek Bio acquired the rights to brequinar from BMS. Brequinar has been investigated as an immunosuppressant for preventing rejection after organ transplant a
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Brequinar
date created:
2020-02-12T08:53:48Z
date modified:
2024-08-27T02:48:33Z
main entity:
{"identifier":"Q27075486","url":"https://www.wikidata.org/entity/Q27075486"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4a/Brequinar_Structural_Formula_V1.svg","width":486,"height":341}
fields total:
13
integrity:
16