Bottom-up proteomics

id: bottom-up-proteomics-272-9146478
title: Bottom-up proteomics
text: Bottom-up proteomics is a common method to identify proteins and characterize their amino acid sequences and post-translational modifications by proteolytic digestion of proteins prior to analysis by mass spectrometry. The major alternative workflow used in proteomics is called top-down proteomics where intact proteins are purified prior to digestion and/or fragmentation either within the mass spectrometer or by 2D electrophoresis. Essentially, bottom-up proteomics is a relatively simple and rel
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Bottom-up_proteomics
date created:
date modified: 2023-11-08T06:06:54Z
main entity: {"identifier":"Q4949102","url":"https://www.wikidata.org/entity/Q4949102"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/f/f6/Top-down_vs_bottom-up_proteomics_image.tif","width":1436,"height":2495}
fields total: 13
integrity: 14

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