Boekelheide reaction

id: boekelheide-reaction-262-7603714
title: Boekelheide reaction
text: The Boekelheide reaction is a rearrangement of α-picoline-N-oxides to hydroxymethylpyridines. It is named after Virgil Boekelheide who first reported it in 1954. Originally the reaction was carried out using acetic anhydride, which typically required a period at reflux (~140 °C). The reaction can be performed using trifluoroacetic anhydride (TFAA), which often allows for a room temperature reaction.
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category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/Boekelheide_reaction
date created:
date modified: 2022-11-14T23:01:15Z
main entity: {"identifier":"Q16624459","url":"https://www.wikidata.org/entity/Q16624459"}
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fields total: 13
integrity: 13

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