BMS-641988
id:
bms-641988-192-9470426
title:
BMS-641988
text:
BMS-641988 is a nonsteroidal antiandrogen which was developed by Bristol-Myers Squibb for the treatment of prostate cancer but was never marketed. It acts as a potent competitive antagonist of the androgen receptor (AR). The drug was found to have 20-fold higher affinity for the AR than bicalutamide in MDA-MB-453 cells, and showed 3- to 7-fold the antiandrogenic activity of bicalutamide in vitro. It may have some weak partial agonist activity at the androgen receptor. BMS-641988 is transformed b
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/BMS-641988
date created:
date modified:
2023-11-29T05:57:00Z
main entity:
{"identifier":"Q27166776","url":"https://www.wikidata.org/entity/Q27166776"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/5/5d/BMS-641988.svg","width":512,"height":306}
fields total:
13
integrity:
15