Bleomycin hydrolase
id:
bleomycin-hydrolase-234-14356108
title:
Bleomycin hydrolase
text:
Bleomycin hydrolase is an enzyme that in humans is encoded by the BLMH gene. Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. Its biological function is hydrolysis of the reactive electrophile homocysteine thiolactone. Another of its activities is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/Bleomycin_hydrolase
date created:
date modified:
2024-03-19T04:56:50Z
main entity:
{"identifier":"Q12856778","url":"https://www.wikidata.org/entity/Q12856778"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/0/0c/Protein_BLMH_PDB_1cb5.png","width":887,"height":908}
fields total:
13
integrity:
15